WORLD HAEMOPHILIA DAY
Every April 17 ,World Haemophilia Day ,is recognised worldwide to increase awareness of haemophilia and other inherited bleeding disorders. This is a critical effort since with increased awareness comes better diagnosis and access to care for the millions who remain without treatment.
World Haemophilia Day was started in 1989 by the World Federation of Hemophilia (WFH) which chose to bring the community together on April 17 in honour of WFH founder Frank Schnabel’s birthday.
In 2018 the theme is SHARING KNOWLEDGE MAKES US STRONGER.
LEARNING WITH TIMES
Haemophilia is an inherited bleeding disorder where the blood doesn’t clot properly as blood does not have enough clotting factor. A clotting factor is a protein in blood that controls bleeding.These clotting factors work with platelets to cause the blood to become sticky and stop a cut or wound from bleeding.Haemophilia is an inherited condition and passed on to a child by one or both parents. More boys than girls are affected.
Von Willebrand disorder (VWD) is an inherited bleeding disorder. People with VWD have a problem with a protein in their blood called von Willebrand factor (VWF) that helps control bleeding.
The process of blood clotting and then the subsequent dissolution of the clot, following repair of the injured tissue, is termed hemostasis.
The blood coagulation mechanism is a process which generates fibrin when it is activated, which together with the platelet plug, stops the bleeding.Platelets (a type of blood cell) and proteins in your plasma (the liquid part of blood) work together to stop the bleeding by forming a clot over the injury.Platelets become activated by thrombin and aggregate at the site of injury, forming a temporary, loose platelet plug. The protein fibrinogen is primarily responsible for stimulating platelet clumping.To insure stability of the initially loose platelet plug, a fibrin mesh (also called the clot) forms and entraps the plug.
Finally, the clot must be dissolved in order for normal blood flow to resume following tissue repair. The dissolution of the clot occurs through the action of plasmin.